5 Medications Still Prescribed to Seniors—Despite Dangerous Side Effects

It’s easy to assume that if a doctor prescribes a medication, it must be completely safe. But for older adults, that’s not always the case. As the body ages, it processes drugs differently, making certain medications far riskier than they are for younger people. In fact, experts use something called the “Beers Criteria,” a widely accepted medical guideline that identifies drugs that may be inappropriate or dangerous for seniors. Even more surprising, many of these medications are still commonly prescribed today, sometimes out of habit or lack of alternatives. Are you taking any of these five medications? You may want to think twice about it if you are…

1. Benzodiazepines (Like Xanax and Valium) Increase Fall and Dementia Risk

Benzodiazepines are often prescribed for anxiety and sleep problems, but they come with serious risks for older adults. These medications can cause sedation, confusion, and impaired coordination. Studies show they significantly increase the risk of falls, fractures, and even car accidents in seniors. Long-term use has also been linked to cognitive decline and a higher risk of dementia. Despite these concerns, they are still frequently prescribed because they provide quick relief.

2. Anticholinergic Drugs Can Harm Memory and Brain Function

Anticholinergic medications are used for everything from allergies to bladder control and depression. While effective, they block a key brain chemical involved in memory and thinking. These drugs are strongly associated with confusion, delirium, and increased dementia risk in seniors. Even over-the-counter options like diphenhydramine (found in sleep aids and cold medicines) fall into this category. Doctors often recommend avoiding these medications whenever possible in older adults.

3. Sleeping Pills (“Z-Drugs”) Can Lead to Falls and Hospitalizations

Medications like zolpidem (Ambien) and eszopiclone (Lunesta) are commonly prescribed for insomnia. However, they work similarly to benzodiazepines and carry many of the same risks. Seniors taking these drugs face higher rates of confusion, falls, fractures, and emergency room visits. Even worse, they often provide only minimal improvement in sleep quality. Because of this, experts recommend using them cautiously or avoiding them altogether.

4. NSAIDs (Like Ibuprofen) Can Damage Kidneys and Cause Bleeding

Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen are widely used for pain relief. While effective, they can be dangerous for seniors, especially with long-term use. These medications increase the risk of gastrointestinal bleeding, high blood pressure, and kidney damage. The risks are even higher for those over 75 or taking blood thinners. Despite being available over the counter, they are far from harmless for older adults.

5. Muscle Relaxants Can Cause Confusion and Increase Fall Risk

Muscle relaxants are often prescribed for back pain or injuries, but they can be particularly problematic for seniors. These drugs can cause drowsiness, confusion, and dizziness. According to experts, they significantly increase the risk of falls and related injuries. In many cases, their benefits are limited compared to the risks they pose. Safer alternatives, like physical therapy, are often recommended instead.

How to Protect Yourself or a Loved One

Knowing which medications carry higher risks is key, but there are a few additional things you can do to protect yourself.

1. Always ask your doctor if a drug is on the Beers Criteria list or if safer alternatives exist.
2. Request a full medication review at least once a year to identify potential problems.
3. Never stop a medication suddenly without medical guidance, as this can cause withdrawal effects.
4. Small changes, like adjusting dosages or switching medications, can significantly improve safety.

At the end of the day, not all medications are created equal, especially when it comes to older adults. Drugs that seem routine could carry some serious risks, including falls, confusion, and even long-term cognitive decline. What you need is to seek the proper guidance. With that, many of these risks can be reduced or avoided entirely.

Have you or a loved one ever experienced side effects from a medication that surprised you?

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Drew Blankenship

Drew Blankenship is a seasoned automotive professional with over 20 years of hands-on experience as a Porsche technician.  While Drew mostly writes about automotives, he also channels his knowledge into writing about money, technology and relationships. Based in North Carolina, Drew still fuels his passion for motorsport by following Formula 1 and spending weekends under the hood when he can. He lives with his wife and two children, who occasionally remind him to take a break from rebuilding engines.