Ozembic miracle weight loss drug or not?

[QuarterMillionMan]

Oprah has a special tonight at 8 pm ET on ABC on this very topic. I think she will say she is taking the drug. She lost a lot of weight.

[james.hendrickson]

Oprah has a special tonight at 8 pm ET on ABC on this very topic. I think she will say she is taking the drug. She lost a lot of weight.

Is any pill a substitute for a healthy diet and enough good daily exercise?

[QuarterMillionMan]

A pill should not be a substitute for a healthy diet and exercise but if it helps jump start a person's weight loss I say more power to them.

[disneysteve]

A pill should not be a substitute for a healthy diet and exercise but if it helps jump start a person's weight loss I say more power to them.

As long as it's safe. I worked through the whole Fen-Phen fiasco back in the 90s when a popular combination of diet pills was found to be causing heart valve damage and pulmonary hypertension.

Who knows what the long term effects of Ozempic may be. The drug has only been on the market for 6 years and only used for weight loss for less than that.

[QuarterMillionMan]

In the first 15 min segment a woman interviewed said she was obsessed with food. At breakfast she’d already be thinking about lunch. On the drug she no longer is obsessed. I didn’t know they are obsessed like that. I enjoy eating but I’m not obsessed like that woman.

[QuarterMillionMan]

In the second 15 min segment a Dr from Cedars Sinai Los Angeles said GLP-1 drugs works both with the brain and organs to lower food intake. Again I didn’t know some people are obsessed with food. Oprah admitted she takes it too.

[QuarterMillionMan]

My thinking if I were on the drug is short term use and discontinue it once I see results. Not long term lifetime usage. I would use it as an aid the get started only and not rely solely on it.

[QuarterMillionMan]

He said it is the holy grail and they cracked the code w/this drug. He's taken it for 1 year and lost lots of weight. He said the 1st day after taking something in his brain no longer craved food. I think obese people must be obsessed with food and the drug decreases that obsession.

[Like2Plan]

From the important safety information for Ozempic link: https://www.ozempic.com/how-to-take/side-effects.html

Important Safety Information

Do not share your Ozempic^® pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.
What is the most important information I should know about Ozempic^®?


Ozempic^® may cause serious side effects, including:

• Possible thyroid tumors, including cancer. Tell your health care provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, Ozempic^® and medicines that work like Ozempic^® caused thyroid tumors, including thyroid cancer. It is not known if Ozempic^® will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.
• Do not use Ozempic^® if you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Do not use Ozempic^® if:

• you or any of your family have ever had MTC or if you have MEN 2.
• you are allergic to semaglutide or any of the ingredients in Ozempic^®. See symptoms of serious allergic reaction in “What are the possible side effects of Ozempic^®?”.

Before using Ozempic^®, tell your health care provider if you have any other medical conditions, including if you:

• have or have had problems with your pancreas or kidneys.
• have a history of diabetic retinopathy.
• are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if Ozempic^® will harm your unborn baby or passes into your breast milk. You should stop using Ozempic^® 2 months before you plan to become pregnant.

Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and other medicines to treat diabetes, including insulin or sulfonylureas.
What are the possible side effects of Ozempic^®?


Ozempic^® may cause serious side effects, including:

• inflammation of your pancreas (pancreatitis). Stop using Ozempic^® and call your health care provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back.
• changes in vision. Tell your health care provider if you have changes in vision during treatment with Ozempic^®.
• low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Ozempic^® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include: dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery.
• kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration.
• serious allergic reactions. Stop using Ozempic^® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
• gallbladder problems. Gallbladder problems have happened in some people who take Ozempic^®. Tell your health care provider right away if you get symptoms which may include: pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools.

The most common side effects of Ozempic^® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

What is Ozempic^®?


Ozempic^® (semaglutide) injection 0.5 mg, 1 mg, or 2 mg is an injectable prescription medicine used:

• along with diet and exercise to improve blood sugar (glucose) in adults with type 2 diabetes.
• to reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart disease.

It is not known if Ozempic^® can be used in people who have had pancreatitis.
Ozempic^® is not for use in people with type 1 diabetes.
It is not known if Ozempic^® is safe and effective for use in children under 18 years of age.


Please click here for Prescribing Information and Medication Guide for Ozempic^®.




Ozempic^® is a prescription medication.

Novo Nordisk provides patient assistance for those who qualify. Please call 1-866-310-7549 to learn more about Novo Nordisk assistance programs.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

[Like2Plan]

interesting discussion on the side effects found here: https://www.reddit.com/r/unpopularop...olute_garbage/

[ua_guy]

I'd be more interested in discussions about the GLP-1 drugs which are also meant to be prescribed for obesity. Mounjaro? I don't think it's the same as Ozempic. I believe Ozempic is still an off-label prescription for obesity whereas Mounjaro and others are more geared towards it. Could be wrong though.

[Like2Plan]

I'd be more interested in discussions about the GLP-1 drugs which are also meant to be prescribed for obesity. Mounjaro? I don't think it's the same as Ozempic. I believe Ozempic is still an off-label prescription for obesity whereas Mounjaro and others are more geared towards it. Could be wrong though.

It says, "Semaglutide (Ozempic®) is a new once-weekly agonist of glucagon-like peptide-1 receptors (GLP-1 AR)" in the description. (Not sure if that is what you getting at).

[ua_guy]

It says, "Semaglutide (Ozempic®) is a new once-weekly agonist of glucagon-like peptide-1 receptors (GLP-1 AR)" in the description. (Not sure if that is what you getting at).

A quick search says Mounjaro contains tirzepatide, while Ozempic contains semaglutide. In addition, the two drugs have differences in how they work. Mounjaro works as a dual-action GIP and GLP-1 receptor agonist, targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.

If I recall from other research, I believe I found that mounjaro is favored for use in weight loss over Ozempic. But I can't say I truly know what I'm talking about here.

[disneysteve]

A quick search says Mounjaro contains tirzepatide, while Ozempic contains semaglutide. In addition, the two drugs have differences in how they work. Mounjaro works as a dual-action GIP and GLP-1 receptor agonist, targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.

If I recall from other research, I believe I found that mounjaro is favored for use in weight loss over Ozempic. But I can't say I truly know what I'm talking about here.

The whole GLP-1 for weight loss thing mainly started after I left practice, so I'm not well versed on the whole deal, but I was using them for diabetes, their intended purpose. Every drug in a class, any class of drugs, works a little differently than the others, which is why the FDA approves them. They may be more potent. They may have fewer side effects. They may have more convenient dosing schedules. Whatever. I'm not specifically familiar with Mounjaro as it didn't come out until 2022 (I left practice in 2017).

Bottom line on every single weight loss drug in existence, however, is what I said earlier in this thread. The effect is only temporary. It only helps while you continue to take the medicine, and sometimes not even that long if your body develops a tolerance to it. It's just a quick fix, which is what everyone is always looking for. It's not a solution to the problem. You're still going to regain the weight if you don't change your lifestyle.

[ua_guy]

The whole GLP-1 for weight loss thing mainly started after I left practice, so I'm not well versed on the whole deal, but I was using them for diabetes, their intended purpose. Every drug in a class, any class of drugs, works a little differently than the others, which is why the FDA approves them. They may be more potent. They may have fewer side effects. They may have more convenient dosing schedules. Whatever. I'm not specifically familiar with Mounjaro as it didn't come out until 2022 (I left practice in 2017).

Bottom line on every single weight loss drug in existence, however, is what I said earlier in this thread. The effect is only temporary. It only helps while you continue to take the medicine, and sometimes not even that long if your body develops a tolerance to it. It's just a quick fix, which is what everyone is always looking for. It's not a solution to the problem. You're still going to regain the weight if you don't change your lifestyle.

I have to imagine the success rate of people who either set out to change their lifestyle alone, or try to change their lifestyle while taking a drug like that is pretty low, long term. This one really hurts the wallet, too. A colleague of mine was on a program with monjuaro. She had to cover the drug out of pocket and it was a bit over $1,000 per month. Ouch.