My girl cat has a heart murmor, so when we got her, we were going to hold off on spaying just because the heart murmor may cause complications during the surgery. She's an indoor cat and our other cat is neutered so no risks for kittens. A few months later she went into heat and I couldn't stand all her meowing/groaning so we took her in and took the risk. She made it out fine and everyone is happier (including her!)
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